March 5th 2025
BLP-003, currently being evaluated for treatment-resistant depression and alcohol use disorder, today announced their global phase 2b clinical trial has completed patient enrollment.
Severe Temper Outbursts in a 10-Year-Old Girl
March 6th 2012The responsibility for improvement was placed on psychiatrists: diagnostic skills had to be improved and patients and their families and caregivers as well as the general public needed to be better educated about the disorder and treatment options.
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History of a Suicide: My Sister’s Unfinished Life
February 10th 2012Mostly prose with effective inclusion of poetry, author Jill Bialosky adds an important survivor’s perspective in her book of her sister's suicide. To clinicians in particular, the book may serve as a window into the psychic lives of those left behind following a tragic end.
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An Evidence-Based Practice of Psychoeducation for Schizophrenia
February 8th 2012Schizophrenia is often characterized by lack of insight, treatment nonadherence, and poor prognosis. However, research suggests that patients with schizophrenia benefit immensely from learning about their illness.
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While research suggests that cannabis use can induce an acute psychotic state, there is controversy about whether it may precipitate psychotic disorders, such as schizophrenia. These authors offer an update on this important issue and provide clinically useful recommendations.
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Two Fallacies Invalidate the DSM-5 Field Trials
January 10th 2012The designer of the DSM-5 Field Trials has just written a telling commentary in the American Journal of Psychiatry. She makes what I consider to be 2 basic errors that reveal the fundamental worthlessness of these Field Trials and their inability to provide any information that will be useful for DSM-5 decision making.
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Is the Criticism of DSM-5 Misguided?
December 22nd 2011Critics of DSM-5 argue that the expansion of diagnostic criteria may increase the number of “mentally ill” individuals and/or pathologize “normal” behavior, and lead to the possibility that thousands-if not millions-of new patients will be exposed to medications which may cause more harm than good.
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Sexual Minority Identity Development
December 16th 2011Sexual identity development is a complex, multidimensional, and often fluid process. One must consider cognitive, social, emotional, cultural, and familial complexities among other aspects of the individual’s experience to contextualize a narrative concerning sexual identity development.
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How We Age: A Doctor’s Journey Into the Heart of Growing Old
December 7th 2011In his book, How We Age: A Doctor’s Journey Into the Heart of Growing Old, Dr Marc Agronin helps reduce the stigma of ageism and provides clinical guidance for seasoned geriatric psychiatrists, primary care clinicians, and medical students alike.
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DSM-5: APA Responds to American Counseling Association Concerns
November 24th 2011On November 21, 2011, John Oldham, MD, president of the American Psychiatric Association (APA), wrote a response letter to Don W. Locke, EdD, president of the American Counseling Association, who had some concerns with proposed revisions for DSM-5.
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DSM-5: Petitions, Predictions, and Prescriptions
November 22nd 2011Some months ago, I received a stern admonition from my family doctor. My fasting blood sugar of 99 mg/dL was “right on the border”, he said, and I had better work on bringing it down. “But,” I protested, “when I was in medical school (in the 70s), the normal FBS range went up to 110 mg/dL!” "Well,” he replied a bit huffily, “they changed the criteria!”
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Treating Mental Illness Before it Strikes
October 28th 2011Psychotic episodes are devastating for the individuals who have them, their friends, and families. Wouldn’t it be wonderful if individuals could receive treatment before the first psychotic episode strikes, so that it could be avoided altogether?
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More Questions For Professor McGorry Arrive From Australia
October 8th 2011I have previously framed a series of questions inviting Professor McGorry to state clearly his current positions on: the accuracy and suitability of attempting to predict psychosis; the types of preventive interventions that he believes are indicated and those (perhaps antipsychotics) that clearly are not . . .
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Familial Influences on Adolescent Substance Use
October 8th 2011Substance use disorders are associated with significant morbidity and mortality that affects individuals and their families. Preventing the onset of an SUD in adolescence remains a critical area of clinical and public health significance.
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