March 5th 2025
BLP-003, currently being evaluated for treatment-resistant depression and alcohol use disorder, today announced their global phase 2b clinical trial has completed patient enrollment.
Effects of New Antipsychotics and Adjunctive Therapy for Schizophrenia (Video: 4:05 minutes)
August 21st 2012What effect has the new antipsychotic Latuda had in patients with psychosis? Is a mood stabilizer as an adjunctive therapy necessary for schizophrenia or is the use of an antipsychotic alone sufficient?
Read More
Effective Personalized Strategies for Treating Bipolar Disorder
August 2nd 2012Effective personalized treatment recognizes bipolar disorder as a biopsychosocial disorder, but mood-stabilizing medications are the backbone of treatment. These medications fall into 3 categories: lithium, antikindling/antiepileptic agents, and second-generation antipsychotics.
Read More
Introduction: Dementia, Delirium, Depression, Drugs, and Driving
July 28th 2012Of the 3 informative articles included in this special geriatric collection, 1 offers a perspective on the treatment of depression that does not focus on somatotherapy. The others remind us of 2 additional geriatric Ds of importance: drugs and driving.
Read More
How to End a Psychiatric Epidemic: The Redemption of Psychiatry
June 12th 2012In light of our problems and uncertainties about the state of current psychiatry, or perhaps because of them, what might describe good psychiatry? Following are some suggestions for what we, as psychiatrists, can do.
Read More
Spitzer Recants: Why Can’t the APA Admit Mistakes and Correct Them?
May 31st 2012Let’s compare Dr Robert Spitzer's apology to the gay community with the stonewalling that has characterized every step in the development of DSM-5. The American Psychiatric Association has a lot to apologize for-but instead maintains a defensive posture that prevents insight and self-correction.
Read More
Wonderful News: DSM-5 Finally Begins Its Belated And Necessary Retreat
May 5th 2012For the first time in its history, DSM-5 has shown some flexibility and capacity to correct itself. Hopefully, this is just the beginning of what will turn out to be a number of other necessary DSM-5 retreats.
Read More
Definitive Study Rejects the Diagnosis of “Psychosis Risk” and Finds No Treatment Benefit
April 17th 2012An excellent study has killed two birds with one stone. It is a clear caution against the DSM-5 proposal for a psychosis risk syndrome and it should temper enthusiasm for rushing ahead with "ultra high risk" prevention programs.
Read More
Does Evidence-Based Medicine Discourage Richer Assessment of Psychopathology and Treatment?
April 5th 2012The paradigm for modern psychiatry is evidence-based medicine (EBM)-it represents proven treatments for defined diagnoses. But there are major problems with this position, starting with the fact that while they are superior to placebo, evidence-based treatments too often are ineffective.
Read More
DSM-5 in the Homestretch-1. Integrating the Coding Systems
March 8th 2012With DSM-5 scheduled for publication a little more than a year from now, we may safely assume that, barring unannounced surprises from, say, the APA Scientific Review Committee, what we will see on the DSM-5 Web site is what we will get. With that in mind it’s time to review what we will indeed get.
Read More