Antidepressants, Part 2: Kinetics, Dynamics, Mechanisms of Action, and the Future
November 20th 2017The author explores the significant pharmacokinetic and pharmacodynamic heterogeneity of current antidepressants and reviews the many potential drug targets that exist-with a focus on the serotonin system.
Now’s the Time for the Bio-Psycho-Social-Environmental Model
November 2nd 2017Here's a model that can stimulate psychiatrists to understand and address denial of global warming, the cognitive dissonance and guilt of our own responsibility, and the role of resilience in adapting to environmental changes.
The authors review basic neuroendocrine function and the evidence base of hormonal contribution to psychiatric symptoms in PCOS, PMDD, and perimenopause. They also offer strategies for psychiatrists for both clinical assessment and management of women with neuroendocrine dysfunction.