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Translational Research: Pathway to Improved Practice?Advances in basic behavior and neuroscience research have been stunning, but until quite recently, efforts to encourage the clinical application of new knowledge have not kept pace. To aid in applying new knowledge to important public health issues, the National Institutes of Health has placed emphasis on "translational research," which aims to provide a bridge between basic research and clinical care. Particularly promising areas of study are highlighted.
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Premenstrual Dysphoric Disorder and Psychiatric ComorbidityDiagnostic Dilemmas-Effective Treatment Approaches
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The Existential Fallout of COVID-19During the pandemic, Albert Camus’ existential novels have become newly popular—and with good reason.
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Artists and Psychiatrists-or the “Art” of PsychiatryArt theory from the 20th century onward-despite the latter day efforts at denial-was nearly indistinguishable from psychoanalytic theory, and it parallels the philosophical struggles and pains that continue to plague psychiatry.
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Assessment and Diagnosis of Posttraumatic Stress DisorderThis article, based on a comprehensive review by Weathers and associates, provides a selective and brief summary of trauma and PTSD assessments in adults.
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Mini Quiz: Narcissistic Personality DisorderWhat is the clinical approach to pathological narcissism and narcissistic personality disorder?
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You Can't Beat the ScreensKids will find the screens. Health care providers should join them in order to supply the most helpful digital treatments.
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“Switching” of Mood From Depression to Mania With AntidepressantsMood switching is not uncommon and it is much more prevalent in depressed juveniles than in depressed adults, and there is a large apparent excess of antidepressant-associated switching over reported spontaneous diagnostic changes to bipolar disorder. Details here.
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PatientsLikeMe: Crowdsourced Patient Health Data as a Clinical Tool in PsychiatryPatients want to know what to expect with a given treatment, how their experiences compare with those of others, or whether they are alone in coping with their conditions. Who best to answer these questions than others like them?
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Psychopharmacologic Therapy in Pregnancy: Effects on NewbornsThere is a tendency to avoid psychiatric medications during pregnancy, but the high prevalence of psychiatric disorders in pregnant women means that women and their physicians must make impromptu decisions regarding the initiation or continuation of drug therapy.
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Preventive Interventions for Children of DivorceStudies have shown that children of divorced parents may suffer more mental health problems, particularly conduct disorders. What programs might be effective in helping these children deal with the stress of their parents' divorce? Are there effective programs to teach parents better coping skills?
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Manual of Inpatient PsychiatryI would recommend it for medical students who have been thrust into the role of primary decision maker for their patients, and clinicians who would appreciate a pocket supervisor to help them make treatment decisions.
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Are We Overdiagnosing and Overtreating ADHD?This article speaks to the care with which ADHD must be diagnosed and managed to reduce the significant negative impact of the disorder on the individual, family, and society.
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Bereavement, Grief, and Depression: Clinical Update and ImplicationsAn in-depth CME on DSM-5 criteria for persistent complex bereavement disorder and the clinical management of pathological reactions to the death of a loved one.
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The Link Between Psychotic Disorders and Substance UsePsychotic disorders are a group of syndromes characterized by positive symptoms, including hallucinations, delusions, and thought disorder; and negative symptoms, including mood symptoms, social withdrawal, and reduced motivation. Cognitive deficits also appear with psychotic disorders. Psychotic disorders rank 22nd in the World Health Organization's list of worldwide causes of disability. This ranking is adjusted for the relatively low lifetime prevalence rate for psychosis; the perceived burden of the disease on those affected with psychotic disorders, as well as their relatives and caregivers, is much higher.
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Differential Diagnosis of Postpartum PsychosisNew mothers may present to the emergency department (ED) with symptoms ranging from mild anxiety to severe psychosis. Postpartum psychosis has abrupt onset and severe symptoms and usually occurs in the immediate postpartum period. Patients who have had a previous episode of postpartum psychosis or have first-degree relatives with postpartum psychosis or bipolar disorder are at higher risk.
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Symposium on Psychology and National Security at the Italian EmbassyThe Embassy of Italy in Washington, DC recently hosted the first of 2 workshops on “Leaders and Terrorists: Psychological Perspectives on National Security.”
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Monoaminergic Treatment of SchizophreniaAlthough several clinical studies suggest that cognitive impairments in schizophrenia are associated with reduced stimulation of dopamine receptors in the prefrontal cortex, mounting evidence suggests that other monoaminergic neurotransmitter systems may also be involved. We provide an overview of neurotransmitters that hold promise as therapeutic interventions for the cognitive deficit in schizophrenia.
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Bereavement, Grief, and Depression: Clinical Update and ImplicationsAn in-depth CME on DSM-5 criteria for persistent complex bereavement disorder and the clinical management of pathological reactions to the death of a loved one.
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Bipolar Disorder: Keys to Improving ComplianceNon-adherence to prescribed medication by patients with psychiatric disorders is one of the greatest challenges reported by clinicians.
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Special Report Chair Discusses SuicideIn this podcast, Dr Caine discusses the many issues associated with suicide and touches on specific articles in this Special Report.
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SSRIsMany of the advantages of the MAOIs are seen with selective serotonin reuptake inhibitors, which have become the drugs of choice in the treatment of panic disorder.
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Botulinum Toxin for Depression? Emotional ProprioceptionIf larger trials confirm the strong antidepressant effects observed so far, botulinum toxin may become a standard therapeutic addition to the psychiatric armamentarium.
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Understanding the Differences Between Impulsivity and CompulsivityA review of targeted treatment strategies for symptom domains when impulsivity and compulsivity become dysfunctional.
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Anthropology-Informed Business Principles for Brain HealthThe key to addressing mental health may lie in business innovation theories.
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New Insight Into the Neurobiology of DepressionCertain aspects of depression result from maladaptive stress-induced changes in reward circuits of the brain.
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Anxiety Disorders With Comorbid Substance AbuseAnxiety disorders occur in 18% to 28% of the US general population during any 12-month period. In anxiety disorder, there is a 33% to 45% 12-month prevalence rate for a comorbid substance use disorder (SUD).
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A Psychiatrist's Journey from Parent to Founder of Research Advocacy OrganizationIn 1988 I was working as a general adult psychiatrist with a specialty in addictions. One day, a newly referred patient came to my office accompanied by his mother. Although he was well groomed, he was distinctly "nerdy." When I inquired about his chief complaint, his mother quickly explained that, although he had graduated from community college, he was unable to secure a job interview due to his obsessing on the details of his resume.
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Treatment-Resistant Mood Disorders: A Psychodynamic ApproachIn this podcast, Dr Eric Plakun give an overview of key points and psychodynamic principles on treatment-resistent mood disorders, based on research and clinical experience.
