SPOTLIGHT -
Clinical Insights: First Case Analysis of MDD
Experts use a major depressive disorder (MDD) patient case to provide clinical insights on managing MDD, and how they would educate patients about their condition.
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Eating Disorders and Emerging Neuroscience
Don't miss this ACNP 2023 Annual Meeting session!
Examining New Agents for MDD Treatment (Esketemine)
Clinicians wrap up their discussion of three new agents approved for the treatment of major depressive disorder (MDD).
Examining New Agents for MDD Treatment (Zuranolone)
Clinicians continue their discussion of three new agents approved for the treatment of major depressive disorder (MDD).
Examining New Agents for MDD Treatment (AXS-05)
Clinicians begin their review of three new agents approved for the treatment of major depressive disorder (MDD).
Love After Love
"You will love again the stranger who was your self."
Current Landscape of Rapid-Acting Therapies for MDD
Experts highlight the current and prospective therapies for patients with MDD, highlighting key similarities and differences in patient pathophysiology, drug onset of action, and overall therapeutic limitations.
Anhedonia and Cognitive Dysfunction: Glutamate Modulation's Impact
Experts discuss the impact of targeting glutamate receptors, highlighting its positive effects for patients with anhedonia.
Shifting Paradigms: The Future Role of Rapid Acting Antidepressants
Experts discuss the need to review current clinical guidelines in light of the need for rapid-acting treatment, especially as first-line treatments for some patients.
Hopeful Horizons: The Potential of Rapid Acting Therapies in MDD
Clinicians discuss the particular benefits of rapid-acting agents for major depressive disorder (MDD), highlighting the gap glutamate-modulating agents fill in targeted therapies.
Targeting Glutamate Receptors in MDD Treatment
Experts continue their discussion on the role of glutamate receptors, explaining their role in stimulating neuroplasticity and neurogenesis.
Giving Thanks to Those Who Furthered My Career
Who helped your career?
Cognitive Wellness: The Potential of Glutamate Modulation for MDD
Clinicians discuss the effects of glutamate modulation on neuroplasticity, memory, and cognitive function, highlighting their role in improving overall wellness for their patients.
Neurotransmitter Ballet: NMDA and AMPA in MDD Management
Experts highlight the role of NMDA and AMPA receptors in major depressive disorder (MDD) and how new therapies are targeting novel mechanisms of action.
Glutamate's Rapid Impact: A New Approach to MDD Management
Clinicians discuss past treatment options compared to novel glutamate-modulating agents, highlighting their rapid onset of symptom relief.
Navigating Major Depressive Disorder (MDD): The Role of Glutamate
Experts discuss the significance of glutamate in major depressive disorder, highlighting its links to neuroplasticity and stress.
"How JFK Killed My Father"
"Hat factories closed quiet as prayer books, and loss lingered in my father’s guts like unswept garbage after a big parade..."
Giving Thanks to the Founders of My Career
Who in your life are you grateful for?
Perhaps the World Ends Here
"Perhaps the world will end at the kitchen table, while we are laughing and crying, eating of the last sweet bite."
The Therapeutic Nature of Kindness
Be kind!
Responding to Change
How do you respond to change? What does properly adjusting to change acquire?
I Knew a Woman
"Of her choice virtues only gods should speak, Or English poets who grew up on Greek (I’d have them sing in chorus, cheek to cheek)."
Now Is the Time for Psychiatrists
We need psychiatrists now more than ever...
Land Ho
"I know I have the blood of survivors coursing through my veins; I know the lament of our loss must warm us again and again down in the belly of the whale..."
Is This Really the Best of All Possible Worlds?
Let's try to make the world a better place.
The First and Only 5HT1a Receptor Agonist for Major Depressive Disorder
Gepirone, the first and only oral selective 5HT1a receptor agonist for the treatment of major depressive disorder in adults, is expected to arrive in early 2024.
Evening Hawk
"His wing Scythes down another day, his motion Is that of the honed steel-edge, we hear The crashless fall of stalks of Time."
Closing Thoughts on the Treatment of MDD
Roger S. McIntyre, MD, FRCPC, and Carmen Kosicek, MSN, PMHNP-BC, discuss the future of MDD treatment and share closing thoughts.
Practical Considerations of Zuranolone Use in Treatment of MDD
Carmen Kosicek, MSN, PMHNP-BC, shares tips with patients about the use of zuranolone to treat MDD.
Colorful Autumn Leaves Can Prepare Us for Death and Dying
What do autumn leaves signify?