March 27th 2025
The prevalence of tobacco use in schizophrenia is over 60%—3 times that of the general population. However, the reason for the high prevalence of tobacco use in schizophrenia remains largely unknown.
From the Streets to the Rx Pad: Do Party Drugs Have a Place in the Medical Office?
October 3rd 2013Can drugs be categorized as good (eg, medicinal), bad (eg, recreational with deleterious side effects and addiction issues), or is there a middle ground? That was the underlying theme in a lecture at PsychCongress, “Perils and Promise of Psychoactive Drugs: A Focus on Harm Reduction Psychiatry.”
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Treating the “Mind” Versus the “Brain” in Substance Dependence
June 25th 2013As we accumulate a greater war chest of patient experiences, we can better apply our skills as physicians to fill a space once occupied with alcohol-lubricated decision-making with smooth yet sober coping strategies.
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A New Report on Pain in America: Like Déjà Vu All Over Again
December 2nd 2011The report notes that pain is a significant public health problem that affects more than 100 million Americans, costs our society at least $560 to $659 billion annually, and can be severely detrimental to the lives of sufferers.
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Familial Influences on Adolescent Substance Use
October 8th 2011Substance use disorders are associated with significant morbidity and mortality that affects individuals and their families. Preventing the onset of an SUD in adolescence remains a critical area of clinical and public health significance.
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Which tool is helpful in screening for sexual addiction? Is the symptom severity in women treated for substance abuse generally equivalent to that of males? Structural abnormalities in which brain areas have been associated with substance abuse? These questions and more in this quiz.
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Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence
June 9th 2011The COMBINE study was only one trial designed by academics to maximize internal scientific validity. It excluded individuals with other significant psychiatric and medical illnesses (more often the rule than the exception in some clinical settings)-individuals deemed too severely ill or who needed hospitalization.
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Introduction: Comorbidity, Cognition, and Pharmacotherapies
June 9th 2011In this Special Report, Helen M. Pettinati, PhD, and William D. Dundon, PhD, discuss prevalence, assessment, clinical features, and treatment issues with respect to individuals with co-occurring major depression and alcohol dependence.
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Self-medication for Anxiety Increases Risk for Substance Use Disorders
May 25th 2011Patients with anxiety disorders who self-medicate with alcohol or drugs may be increasing their risk for developing incident substance use disorders, according to a study presented at the American Psychiatric Association’s recent annual meeting.
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Does MDMA Have a Role in Clinical Psychiatry?
May 7th 2011Like every drug or technology that has therapeutic value, MDMA (3,4-methylenedioxymethamphetamine) has potential risks and benefits. Unlike most other drugs under clinical investigation, MDMA has a complex and controversial history that has delayed dispassionate scientific investigation into its therapeutic use.
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Marijuana Withdrawal Syndrome: Should Cannabis Withdrawal Disorder Be Included in DSM-5?
April 28th 2011DSM-IV, published in 1994, did not include a cannabis withdrawal disorder diagnosis. DSM-IV-TR clearly stated the reason for the omission: “Symptoms of possible cannabis withdrawal . . . have been described in association with the use of very high doses, but their clinical significance is uncertain.”1
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The Link Between Substance Abuse, Violence, and Suicide
January 21st 2011Emerging research suggests that some individuals with particular types of substance use and abuse may be more likely to engage in suicidal behaviors. For example, those who use opiates, cocaine, or sedatives may have a noticeably higher risk of suicide than those who use other drugs.
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Does Research Support “Craving” as a Core Symptom of Substance Use Disorders in DSM-5?
January 11th 2011Recently, the Substance Use Disorder Work group of the DSM-5 announced the inclusion of “craving” in the diagnostic criteria for all substance use disorders despite its lack of empirical support from the very analyses conducted by that Workgroup. In addition, no detailed literature review supports the decision to make “craving” a core symptom of Substance Use Disorder syndromes.
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Opiate Substitution Treatment Found to Reduce Mortality Rate in Addicts
October 28th 2010A recent study reports that patients have a greater chance of survival when given opiate substitution treatment (OST) for over 12 months. Although there has been a 2-fold increase in opiate prescriptions in the past 10 years, the mortality rate from OST has fallen, making it a viable treatment for opiate abusers.
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