Brian Miller, MD, PhD, MPH

Does the “early bird get the worm”? Researchers investigated long-term outcomes with an early-switch long-acting injectable antipsychotic in patients with schizophrenia using a population-based cohort.

Do your patients have abnormal thyroid indices? Researchers performed a comparison of thyroid function based on mood state in drug-naïve patients with bipolar disorder.

The eyes are a window to the brain. Researchers performed a nationwide cohort study of the risk of retinal disease in patients with bipolar disorder.

Researchers investigated population-level phenotypes occurring before and after diagnosis of schizophrenia using a large health insurance claims dataset.

Researchers performed a meta-analysis of the prevalence of type 2 diabetes, impaired fasting, glucose, and general and abdominal obesity in bipolar disorder.

Adjunctive metformin in bipolar disorder. Researchers performed a randomized clinical trial of treating insulin resistance to improve clinical outcomes in treatment-resistant bipolar depression.

“In the general population, insomnia is associated with greater cognitive impairment, but its association (and potential sexual dimorphic effect) in schizophrenia is less clear.”

Researchers performed a randomized controlled trial of a high n-3, low n-6 polyunsaturated fatty acid diet in bipolar disorder.

Lithium for bone health? Researchers performed a retrospective cohort study to evaluate the effects of lithium on risk of osteoporosis in bipolar disorder.

Predicting mania versus psychosis: Researchers performed a retrospective study of prodromal symptoms, risk factors, and vulnerability markers in first-episode mania and psychosis.

Researchers performed an RCT of pramipexole for patients with bipolar disorder and cognitive impairment.

Are you taking your medication? Researchers performed a nationwide register-based study of primary antipsychotic nonadherence in schizophrenia.

Researchers performed a systematic review and meta-analysis of paternal and maternal age and risk of bipolar disorder in the offspring.

Researchers performed a systematic review and meta-analysis of life expectancy and years of potential life lost in bipolar disorder.

Findings from a recent study can help clinicians optimize antipsychotic dosing during acute illness exacerbations.

Is sustained treatment with clozapine safe during the COVID-19 pandemic?

Thinking about sex and sleep in schizophrenia: Researchers performed a large cross-sectional study of sex differences in insomnia and cognition in chronic schizophrenia.

Should we go up? Researchers performed a dose-response meta-analysis of randomized controlled trials in acute phase schizophrenia.

Does clozapine increase the risk of severe COVID-19 infection? Researchers performed a larger register-based cohort study of this association.

Put out your cigarette. Researchers performed a cohort study of the impact of cigarette smoking on life expectancy in schizophrenia, schizoaffective disorder, and bipolar disorder.

Comorbidity or medication adverse effect? Researchers performed a nested case-control study of new-onset obsessive-compulsive disorder following antipsychotic use in schizophrenia.

Unintentional overdose with antipsychotics plus opioids. Researchers performed a population-based cohort study of the risk of overdose associated with co-prescription of antipsychotics and opioids.

All in a good night’s sleep? Researchers performed a pharmacovigilance study of second-generation antipsychotics and mood stabilizers as the suspected agent of psychiatric adverse drug reactions (insomnia and suicide/ideation/behavior/death).

A new research study, based on over 800,000 mothers and children, tests the hypothesis.

What are the risk factors for and prevalence overweight and obesity in patients with first-episode drug-naïve major depressive disorder?

Doctor, can I have an extra cup of caffeine? Researchers performed a systematic review of studies of caffeine consumption and clinical symptoms in patients with bipolar disorder.

A growing body of scientific literature makes the case.

A recent study dives into the data.