Brian Miller, MD, PhD, MPH

Researchers performed a head-to-head trial of vortioxetine versus desvenalfaxine in patients with depression and partial response to SSRIs.

Researchers investigated associations between medications with potential depressive symptom adverse effects and the level of depressive symptoms in a large survey study. Here’s what they found.

What is the nature of the relationship between psychosis and sleep disorders?

Does early improvement in insomnia predict response to pharmacotherapy in psychotic depression? Authors performed a secondary analysis of a randomized clinical trial.

What is the risk of diabetes, hypertension, or hyperlipidemia with antipsychotic polypharmacy in patients with schizophrenia? Researchers investigated these associations in a population-based prospective cohort study.

Is psilocybin a viable treatment for MDD? Researchers performed a phase 2, double blind trial of single-dose psilocybin in patients with treatment resistant depression.

“Are my other medications making my depression worse?” Researchers investigated associations between medications with potential depressive symptom adverse effects and the level of depressive symptoms in a large survey study.

Do SSRIs impact on the antidepressant efficacy of psilocybin? Researchers performed an open-label trial of single-dose psilocybin in patients with TRD who were taking SSRIs.

Adjunctive rTMS for treatment-resistant depression? Researchers performed a meta-analysis of 19 randomized sham-controlled trials.

What is the association between cannabis use disorders and schizophrenia? Researchers used a nationwide register-based cohort study to investigate these associations.

Researchers investigated the prevalence and correlates of sleep disorders in patients with first-episode psychosis.

According to recent research, sleep problems were a common symptom in a large study of patients with first-episode psychosis.

What is the association between the gut microbiome and response to SSRIs in patients with depression?

Doctor, how will this medication affect my child’s growth? Researchers performed a register-based study of ADHD, ADHD medication, and height.

Test your knowledge on the latest research in sleep issues and schizophrenia.

Check out the evidence for a modest effect over 1 year of clozapine dose on weight.

Gestational and neonatal risk factors for bipolar disorder? Researchers investigated these associations in a nationwide cohort with register-based data.

Metabolic mediators of anxious depression? Researchers investigated metabolic correlates of overweight/obesity in patients with MDD.

Researchers used an observational cohort study to investigate a potential causal association.

Researchers investigated relationships between sleep problems, suicidal ideation, and psychopathology in patients with first-episode psychosis.

Looking to stay up to date on MDD research? This research collection reviews outcomes on metabolic abnormalities, biomarkers, and more.

What is the connection?

What are the key diagnostic differences between schizophrenia and schizoaffective disorder?

A gut feeling? Researchers analyzed the gut microbiome in major depression disorder and its modulation by SSRI antidepressants.

Research investigated this association in a prospective cohort study.

What are the psychiatric and non-psychiatric correlates of tobacco smoking status in bipolar disorders? Researchers investigated these associations in a large patient cohort.

Do ADHD symptoms impact smoking cessation outcomes? Researchers performed a randomized controlled trial of varenicline for tobacco cessation in adolescents and young adults.

Researchers investigated sleep disturbances in individuals at ultra-high risk of psychosis.

Caffeine use is higher in smokers and in adults with serious mental illness. How does this impact patients with bipolar disorder and schizophrenia?

Researchers performed a nationwide register-based cohort study of patients treated with lithium in Finland.