Schizophrenia/Psychosis

How can you apply the framework and philosophy of evidence-based medicine to the use of antipsychotic medication? Here to discuss is Leslie L. Citrome, MD, MPH.

Most persons who use CAM modalities to self-treat a mental health problem take prescription antidepressants concurrently. Combined use can result in serious supplement-drug interactions.

What if someone with “prescriptive privileges” looked at superficial symptoms only, and ordered antipsychotics without considering the bigger picture?

How prevalent is schizophrenia? Take the quiz and learn more.

This article summarizes efforts to develop neurocognitive enhancement drugs administered individually or as an adjunct to other antipsychotics and cognitive remediation.

Obesity is one of the most common physical health problems in individuals with psychiatric conditions and contributes to excess medical morbidity and mortality. Several classes of psychotropic medications, particularly atypical antipsychotics, cause weight gain. While these issues pose challenges to optimal health, the good news is that there are solutions and emerging strategies.

Surprisingly, psychiatrists and psychiatric nurses “were just as likely” as their primary care counterparts to display negative biases toward individuals with schizophrenia seeking general medical care.

The aggregation of psychiatric diagnoses in individual psychiatric patients, ie, the presence of multiple disorders in one individual, is a curious and sometimes disturbing observation in psychiatry.

This article reviews some of the most recent findings in genetics and pharmacogenetics of schizophrenia-especially those with clinical implications.

Genetics seems to be a subject of particular interest for everyone. This article explores how the current state of knowledge regarding genetics might be used to help psychiatrists diagnose psychiatric disorders or predict their onset.

"Psychiatric diagnosis is certainly imperfect -- but so is much of diagnosis throughout medicine. And whatever the current limitations, psychiatric diagnosis is useful and essential. There are no 'paradigm shifts possible til we learn a lot more. To imply otherwise is misleading and confusing to patients."

Two problems persist in the treatment of severe mental illness that constitute a barrier to effective patient-centered care: excessive reliance on a limited number of antipsychotic medications at the expense of other effective treatments, and the underutilization of other evidence-based treatment options.

The flat out rejection of DSM-5 by National Institute of Mental Health is a sad moment for mental health--and an unsafe one for our patients. The APA and NIMH are both letting us down, failing to be safe custodians for the mental health needs of our country.

Psychiatrists vary in their eagerness to share therapeutic decisions with patients: some believe that adherence is paramount and paternalism is often necessary to prevent loss of insight with consequent impaired judgment and functional decline. These authors argue in favor of a radically more collaborative style.

How frequently do you find yourself prescribing antibiotics for inpatients with schizophrenia and related psychotic disorders during hospitalization?

This article explains and demonstrates the importance of psychiatric advance directives and the benefits and obstacles involved in implementing them.

President Barack Obama proposed a new research initiative designed to further study and better understand, treat, prevent, and cure brain disorders including Alzheimer disease, traumatic brain injury, autism, posttraumatic stress disorder, and schizophrenia.

When critics of psychiatric diagnosis insist that terms like “schizophrenia” or “bipolar disorder” are inherently stigmatizing, they are unwittingly perpetuating the very prejudice they wish to end. It is time to shine a bright light on this self-fulfilling prophecy.

Medication side effects of weight gain and increased appetite, together with non-adherence often found in persons with schizophrenia, bipolar disorder, and other serious mental illnesses, have challenged clinicians in the past.

While the diagnostic categories of DSM-III and DSM-IV (and soon DSM-5) have provided the basis for much useful research, little has been written about how much of DSM-and how much “evidence-based medicine”-is built on a foundation of fantasy.

Outpatient psychiatry is a critical experience in becoming an independent psychiatrist.

Historically, there has been conflict between psychiatry and religion.

The humanities are a variety of academic disciplines that focus on the human condition with analytic and sometimes speculative methods. This is in contrast to the empirical methods of the natural sciences.

Schizophrenia has long been considered a neurodevelopmental disorder in which onset of diagnostic symptoms in late adolescence or adulthood is the end result of a decades-long interaction between genes and environment that begins in the womb.

A recent symposium brought together some of the nation’s leading experts to talk about promising advances in psychiatry and to address areas where progress has faltered.

This week's news stories: intimate partner violence, gun control and mental illness, eating disorders, and more.

The Clinical Assessment Interview for Negative Symptoms (CAINS) is an effective tool in measuring negative symptoms in schizophrenia, according to a recent study.

It is clear that the prognosis for schizophrenia is much better when patients achieve drug abstinence, including in the domains of depression, quality of life, and community integration.

Emil Kraepelin diagnosed the paranoid, catatonic, and hebephrenic forms of dementia praecox, a disease he created.

Both positive and negative symptoms of schizophrenia combined with those of a mood disorder led to a psychiatric diagnosis; later, a neurological diagnosis of anti–NMDA receptor autoimmune encephalitis was made.