Major Depressive Disorder

Many patients can benefit from herbs with gentler action, fewer adverse effects, and some health benefits beyond their antidepressant effects.

A brief synopsis on how to spot major depression in youth.

As varied as the field of psychiatry itself, our Special Report collections covered issues such as eating disorders, traumatic brain injury, practice management, schizophrenia and depression, complex medical comorbidities, and more. Here's a sampling.

Climate medicine: What was once on the radar of just a handful of physicians has exploded into awareness, alarm, and sometimes debate and skepticism. No matter how you look at it, psychiatrists are on the front lines.

As the aging population grows, depression in older adults is also on the rise. Read the short case and test your knowledge.

Depression predominates across the lifespan in patients with bipolar disorder. Here: A discussion about (and beyond) the four FDA-approved drugs to treat symptoms.

A psychiatrist attempts to stay positive while facing her parents' and loved ones' premature deaths-ever reminding us that hope springs eternal.

Recommendations for patients with serious mental illness to manage their finances safely and conveniently, with as much dignity, privacy, and autonomy as possible.

P values tell half of the story. A result that is statistically significant may actually be clinically irrelevant. More in this video.

In a first-of-its-kind study, researchers from the Icahn School of Medicine at Mount Sinai, Montefiore Health System, and Albert Einstein College of Medicine are working together to examine the link between depression and asthma in older adults.

Doing a review of systems wasn’t “rocket science,” as they say-but it was a classic example of medical science and of why psychiatrists are physicians first.

The chronic and relapsing course of TBI-associated depression poses a challenge to the management of afflicted patients.

A layperson's perspective after deliberating on the meaning of suicide for decades after the loss of his wife.

A teaching moment never to be forgotten, little did the author know that this action on his patient's part would be the harbinger of an amazing career looking after physicians.

Is there a biomarker to predict response to treatment for depression? Take the quiz and learn more.

With a combined 70+ years of clinical experience, the authors discuss scenarios that represent two possible outcomes of discontinuing serotonergic antidepressants.

In a national epidemic of caregiver distress and suicide, what barriers still stand in the way of seeking mental health treatment for medical professionals?

Here is a selection of eight research developments that may impact psychiatric clinical practice in the coming years.

Finding meaning helps to reframe the experiences of our own lives, not as events to hide in shame or guilt, but as experiences that made us physicians we are today.

“Even after the Pittsburgh shootings, our ability to empathize suggests otherwise,” writes Ronald W. Pies, MD, in a commentary regarding the nature and origin of hatred.

New findings from a small study confirm previous research that shows a potential value of EMDR in the management of major depressive disorder.

Three new studies highlight the link between depression and opioid overdoses; “early birds” are less prone to depression; and consuming fish may reduce the risk of depression.

Which treatments have demonstrated strong evidence of effectiveness in the treatment of major depressive disorder?

One of the biggest challenges in treating depression is the ability to select the best treatment for a particular individual from among the many available options.

This is not yet another philosophical discourse arguing against physician-assisted suicide. This piece is about life with dignity-even amidst its raw and ravaging agonies.

Besides being sad, patients who are depressed often feel disgruntled, resentful, or irritable. Such emotions can lead to violence in people who are predisposed to such behavior. Consider the questions in this quiz.

New studies in major depression find VNS improves the quality of life of patients with treatment-resistant depression and two other findings.

A recent study found mindfulness-based cognitive therapy plus treatment-as-usual helped patients who stuck with the program.

This article discusses the peculiarities of emergency psychiatric practice and reviews innovations in models of care delivery designed to overcome the challenges of this subspecialty.

The perils of job insecurity; depression and cardiac risks; the longest-running mental health study; smart drugs that aren’t so smart; heatstroke in psychiatric patients; an autism puzzler; and psychosis and eating disorders.