November 14th 2024
Check out new results of a pharmacokinetics study of AD04, an investigational therapeutic agent for the treatment of alcohol use disorder in patients with heavy drinking.
September 20th 2024
America's policy regarding illegal drugs has been accused of being a failure and being racially biased against blacks and other minorities. The author asserts that while drugs and crime exist in all parts of the society, problem-generating drug use and serious crime are indeed concentrated among the urban poor, some of whom are black. He further explores what this disproportionate drug-related suffering means when it comes to the provision of addiction treatment, law enforcement resources and other responses to the problems spawned by addiction.
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Trying To Solve the Prescription Drug Abuse Equation
February 1st 2001Results from the 1999 National Household Survey on Drug Abuse show significant increases in rates of prescription drug abuse. Other surveys show similar findings. An overview of the most commonly abused drugs and suggestions for preventing abuse are reviewed.
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Addiction and the Eating Disorders
February 1st 2001Although comprehensive theories of addiction recognize the etiological importance of environmental and cognitive factors, it has been widely accepted for many years that addiction is also a brain disease and that individuals differ in their susceptibility to this condition.
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Is ECT Appropriate in Old-Old Patients?
January 1st 2001More patients are reaching the old-old demographic-those age 75 and above-with psychiatric conditions such as treatment-resistant depression. Research has shown that with some careful screening and precautions, ECT is a safe, effective treatment option for these patients.
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Overview of Elder Maltreatment
January 1st 2001As the population ages, psychiatrists will need to take a more proactive role in preventing, diagnosing and treating elder abuse. This article looks at the definition of elder abuse and the history of reporting it, research findings on the effects of abuse on mortality, and needs for the future.
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The Once-Forgotten Factor in Psychiatry: Research Findings on Religious Commitment and Mental Health
October 2nd 2000As previously discussed, new research has made us look much more closely at the influence of religion and spirituality on overall health. Now more than 30 psychiatric residencies including Harvard, Baylor, and Georgetown provide focused training on addressing patients' religious/spiritual beliefs.
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NCDEU Report Part II: Research Methods Considered at NCDEU
November 2nd 1999The methodology of clinical trials was as much of interest as the trial results for investigators gathered at the 39th annual NCDEU (New Clinical Drug Evaluation Unit) Program meeting. This meeting was conducted in June by the National Institute of Mental Health in Boca Raton, Fla.
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NCDEU Report Part II: Research Methods Considered at NCDEU
November 1st 1999The methodology of clinical trials was as much of interest as the trial results for investigators gathered at the 39th annual NCDEU (New Clinical Drug Evaluation Unit) Program meeting. This meeting was conducted in June by the National Institute of Mental Health in Boca Raton, Fla.
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Obtaining Medical Research Grants
November 1st 1999The fiscal year (FY) 1999 budget for National Institutes of Health funding totals more than $15 billion. This figure reflects an increase of 15% over the FY 1998 budget and is $320 million less than President Clinton's requested budget for FY 2000 (Varmus, 1999). The Foundation Center reports the funding from U.S. grant-making foundations in 1998 as $15.4 billion from independent foundations, $2.37 billion from corporate foundations and $1.48 billion from community foundations (Foundation Center, 1999). Additional funds are available from the National Science Foundation (NSF), which has a $3.95 billion budget request for FY 2000, up almost 6% from FY 1999 (NSF, 1999). With all of this available funding, how can medical clinicians and researchers increase their chances of obtaining a medical grant?
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A Patient With Panic Disorder Abetted by a Dependent Personality
November 1st 1999By the time I interviewed Robyn in the emergency room, her panic attack had all but passed. But this 21-year-old woman was still shaken and tearful. This was her first panic attack, and she did not know what hit her. She thought she was having a heart attack. She had a tight feeling in her chest, she was hyperventilating. Her fingers and feet were numb and tingling. She experienced what she called a "closing in feeling." Robyn thought she was going to die.
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Neurobehavioral Consequences of Sleep Dysfunction
October 1st 1999As chief of the division of sleep and chronobiology in the department of psychiatry at the University of Pennsylvania School of Medicine, David F. Dinges, Ph.D., focuses on ways sleep and the endogenous circadian pacemaker interact to control wakefulness and waking neurobehavioral functions such as physiological alertness, attention, cognitive performance, fatigue, mood, neuroendocrine profiles, immune responses and health. In an interview with Psychiatric Times, Dinges discussed neurobehavioral consequences of sleep loss, factors that impair sleeping, the pervasiveness of sleepiness and new ways to manage sleepiness.
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Interventions Aim To Prevent Depression in High-Risk Children
September 1st 1999Children whose parents have been diagnosed with affective disorders are far more likely to be diagnosed with a mental illness-especially affective disorder-than their peers whose parents do not have mood disorders (Beardslee, 1998; Burge and Hammen, 1991; Downey and Coyne, 1990).
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More than 430 psychiatrists, research donors and others gathered in late October for the National Alliance for Research on Schizophrenia and Depression (NARSAD)'s awards dinner in New York City. The black-tie fundraising event was held in conjunction with the organization's 10th annual scientific symposium at which 15 selected NARSAD grantees presented their ongoing research over two days of sessions devoted to basic science, schizophrenia and depression.
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Olanzapine Versus Risperidone Rematch
August 1st 1999One day after Eli Lilly and Company researchers reported finding olanzapine (Zyprexa) superior to risperidone (Risperdal) on some measures in a 28-week comparative study presented to the American College of Neuropsychopharmacology (ACNP) meeting in 1996, Janssen Pharmaceutica Inc. issued a press statement critical of the methodology and results of the study. Janssen then announced it would undertake its own comparative trial. The results of this trial's initial eight-week acute treatment phase were presented at the European College of Neuro-psychopharmacology meeting held Oct. 31, 1998, through Nov. 4, 1998, in Paris. They indicate risperidone has an advantage for positive symptoms such as hallucinations and delusions, and for anxiety/depression in patients with schizophrenia and schizo-affective disorder.
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How AA and Psychotherapy Can Work Together
July 1st 1999Until the last half of this century, there were few if any treatments that seemed consistently effective in responding to the clinical needs of individuals who were abusing or dependent upon alcohol. As a result, support or self-help groups emerged. Alcoholics Anonymous is an extraordinary example of these groups.
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AMA Eliminates Department of Mental Health Abrupt Firing of Director Raises Questions, Concerns
May 1st 1999Only one month after the American Medical Association unveiled a major reorganization of its science and technology departments-one that included the dismantling of its department of mental health-the former director, psychiatrist Larry Goldman, M.D., was fired after he criticized the changes.
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ACNP Focuses on Recent Treatment Advances
May 1st 1999Recent advances in the treatment of mental and addictive disorders, along with research findings in basic neuroscience, molecular genetics and molecular biology that contribute to the understanding of such disorders, were discussed at the American College of Neuropsychopharmacology's 37th annual meeting in Puerto Rico. The following are brief reports from selected presentations.
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Promising Medications for Axis I Disorders
May 1st 1999More than 80 medications are in development to treat mental illnesses, including 18 for depression, 15 for schizophrenia and 16 for anxiety disorders, according to the Pharmaceutical Researchers and Manufacturers of America (1998). Which ones will most likely come to market in the United States?
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Schuckit Addresses State-of-the-Art Addiction Treatments
April 1st 1999Marc Schuckit, M.D., professor of psychiatry at the University of California, San Diego, School of Medicine, examined recent developments in the treatments for alcohol and drug dependence, and examined important changes in DSM-IV's classification of substance use disorder at the 11th Annual U.S. Psychiatric & Mental Health Congress.
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Living Stories: Spiritual Awakenings in Recovery
April 1st 1999DeAndra's story: I came into the rooms and realized after a while that I had the attitudes and behaviors of an addict way before I ever picked up a drug. I remember growing up and being at my family's parties, [where] my aunts and uncles would give me and my brothers beer. There are pictures in our photo albums of us, all under 6 or 7, with cans of beer in our hands. At an early age I learned to manipulate to get what I wanted.
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Commentary Alcoholism and Free Will
April 1st 1999Psychiatrists, like the rest of America, continue to have trouble with alcoholic and other addicted patients. We are comfortable when patients want to get better, tell us the truth and come to treatment of their own free will, but alcoholics often don't fit this profile. We respond angrily when patients manipulate us. We are surprised when their sincere desire for help evaporates after we suggest a plan that will bring about real change.
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Behavioral Couples Therapy for Alcoholism and Drug Abuse
April 1st 1999Nearly 25 years ago, the National Institute on Alcohol Abuse and Alcoholism hailed couple and family therapy as "one of the most outstanding current advances in the area of psychotherapy of alcoholism" and called for controlled studies to test these promising methods. Currently behavioral couples therapy (BCT) is the family therapy method with the strongest research support for its effectiveness in substance abuse.
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