SPN-820 Fails to Meet Primary Endpoint in Study of Adults with Treatment-Resistant Depression
February 20th 2025After a lot of recent positive news for SPN-820, a recent phase 2b study shows the novel antidepressant failed to demonstrate a statistically significant improvement on the primary endpoint of change from baseline.
Planned Induction of Labor in a Patient With Acute Late-Pregnancy Psychosis: A Case Report
Consideration of both practical and ethical concerns, as well as an interdisciplinary approach, can lead to better outcomes for pregnant patients with psychosis.
Xanomeline-Trospium as a Novel Agent for Treatment of Psychosis in Schizophrenia
Recent research demonstrated that xanomeline-trospium is more efficacious than placebo in treating positive and negative psychotic symptoms in adults with schizophrenia.
AXS-05 Demonstrates Efficacy and Manageable Adverse Effects in Major Depressive Disorder Treatment
February 12th 2025A pooled analysis of two clinical trials highlights AXS-05’s rapid and sustained effectiveness in reducing depressive symptoms, offering a promising new treatment option for major depressive disorder with a manageable safety profile.
SPN-820 Shows Rapid and Significant Improvement in Major Depressive Disorder Symptoms
February 12th 2025A new phase 2 trial reveals a novel antidepressant delivers rapid symptom relief for major depressive disorder, with patients experiencing significant improvement within just hours of their first dose.