Bipolar Disorder: A Brain-Body Disease

We know there is extensive overlap between bipolar disorder and medical morbidity-including obesity, diabetes, and metabolic syndrome. The real question is why.

Here to talk about the implications of concurrent metabolic problems on the clinical course of bipolar disorder in this first of a 2-part podcast is Roger McIntyre, MD, Professor of Psychiatry and Pharmacology and Head of the Mood Disorders Psychopharmacology Unit at the University of Toronto.

Dr McIntyre is a speaker at this year's PsychCongress in a presentation titled "Bipolar Disorder and Medical Comorbidity: Research and Treatment Implications." (For Part 2 of this podcast series, please click here.)

Further reading:
Baskaran A, Cha DS, Powell AM, et al. Sex differences in rates of obesity in bipolar disorder: postulated mechanisms. Bipolar Disord. 2014;16:83-92.

Reininghaus EZ, McIntyre RS, Reininghaus B, et al. Tryptophan breakdown is increased in euthymic overweight individuals with bipolar disorder: a preliminary report. Bipolar Disord. 2014;16:432-440.

McIntyre RS, Soczynska JK, Liauw SS, et al. The association between childhood adversity and components of metabolic syndrome in adults with mood disorders: results from the international mood disorders collaborative project. Int J Psychiatry Med. 2012;43:165-177.