Suicide rates among American youth have been on the rise over the past 15 years, and suicide is the second leading cause of death among teenagers. Prevention is vital, but what approaches have the best evidence of efficacy?

In this Mental Health Minute, Nakela L. Cook, MD, MPH, discusses 5 studies funded by the Patient-Centered Outcomes Research Institute. The largest assesses the effectiveness of dialectical behavior therapy, while others will look at the unique challenges facing autistic youth, Alaskan natives, and sexual and gender diverse young adults.

Dr Cook is the executive director at the Patient-Centered Outcomes Research Institute.