Vol 35, Issue 7

Recent findings suggest that the magnitude of efficacy for most antidepressants compared with placebo may be more modest than previously thought.

Since the choice of treatments for a primary bipolar I disorder major depressive episode versus a unipolar major depressive episode are significantly different, this information will help guide clinicians in how to proceed.

The most challenging aspect of pseudobulbar affect is differentiating it from depression. Episodes of uncontrollable, sudden, and even inappropriate emotions may point to neurologic or psychiatric conditions.

Despite the scope and magnitude of rising rates of depression and suicide, the field of psychiatry may be witnessing a turning point.

In considering how best to disseminate the many psychotherapeutic techniques to practicing clinicians, the author reviews findings and changes to guidelines on depression treatments.

The use of biomarkers to assist with optimizing treatment decisions for depression has been receiving increasing attention. Here is an overview of the challenges and barriers that must be overcome before therapeutic markers can effectively be utilized in practice.

Walter Benjamin’s suicide is especially interesting as a bridge from the Freudian psychosocial era of hysteria-neuroses to the current era of the borderline-narcissist.

If we fail to cultivate and exercise virtues such as wisdom, curiosity, intellect, aesthetic sensitivity, compassion, empathy, and generosity, we fail to exemplify human flourishing.

Bingeing on news about the latest White House rumpus has escalated exponentially since the election. Whatever their political views, patients are haunted by an inchoate sense that the wheels are coming off the car, with nary a mechanic in site.

In this novel, we join New York consultation-liaison psychiatrist Dr Millard Salter for what he intends to be his final day on earth.

Where are the crusading editorial boards who decide that the inadequacy of mental health care is such a public health emergency that ongoing investigative journalism is needed?

This CME identifies the sources of treatment-resistant ADHD in adults and focuses on preventing misdiagnosis and optimizing treatment.

A novel compound holds promise for addressing cognitive deficits in schizophrenia.

Like the song New York, New York, if we can succeed in reducing suicide in physicians, we can do it anywhere.

The neuroprotective role of resilience in patients with schizophrenia who experienced early childhood trauma is evaluated in this brief update.

More than any other medical specialty, we sometimes feel compelled, and empowered, to treat patients against their will. With this comes two great responsibilities.

The thorny issue of “end-of-life care” is likely to remain controversial in the US, with physicians themselves holding a wide variety of views.

Hypomania is critical to rule out, but hard to pin down. In part 1 of this 2-part series, Dr. Aiken shares his top pearls for making the diagnosis.